HPV genotypes typed with real-time PCR in an Amazonian region of Ecuador
DOI:
https://doi.org/10.36097/rgcs.v3i2.3226Keywords:
HPV, human papillomavirus genotypes, cervical cancer, PCRAbstract
The objective of this study was to characterize the most frequent HPV genotypes in patients seen at a clinical laboratory in the province of Napo, Ecuador, between October 2022 and December 2024. A descriptive, cross-sectional, retrospective study of HPV genotyping results using real-time PCR was conducted. Using non-probabilistic convenience sampling, results were obtained from 192 patients of both sexes residing in the province. The predominant age group was 28-33 years old, female. There were no statistically significant differences between the ages of women and men. Molecular testing showed positive results for HPV (≥1 genotype) in 40.6% of the patients. The three most common genotypes were: HPV 68 (25.6%); HPV 16 (23.1%); HPV 51 (21.8%). HPV 68 was also the genotype with the highest relative frequency and distribution in the PAP test results analyzed. The presence of several high-risk genotypes in all Pap test categories underscores the complexity of HPV epidemiology and highlights the importance of genotypic typing using molecular techniques for adequate risk stratification and clinical decision-making.
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