Electrospinning encapsulation of a majagua flower (Talipariti elatum Sw.) extract in zein for sustained release of bioactive compounds

Authors

DOI:

https://doi.org/10.36097/rgcs.v3i1.3222

Keywords:

Talipariti elatum, bioactive compounds, zein, electrospinning, controlled release, microencapsulation

Abstract

The majagua flower (Talipariti elatum Sw.) is rich in bioactive compounds with antioxidants, neuroprotective, antimicrobial, anticancer, and cardioprotective activity, although they are highly sensitive to degradation during processing and storage. To stabilize them, microcapsules were prepared by electrospinning encapsulation using zein as a protective matrix in three extract concentrations (10, 20, and 30% w/w). FT-IR analysis confirmed zein's ability to encapsulate the extract's bioactive compounds. The morphology of the particles was evaluated by SEM, and the release of compounds was consistent with the Peleg and Korsmeyer-Peppas models. The highest encapsulation efficiency was achieved with 20% w/w (~69%), showing uniform particles and controlled release by diffusion. These results confirm that electrospinning with zein effectively protects the bioactive compounds of the majagua flower, ensuring sustained release and potential biological functionality, with applications in pharmaceutical and nutraceutical formulations.

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References

Aceituno-Medina, M., Lopez-Rubio, A., Mendoza, S., & Lagaron, J. M. (2013). Development of novel ultrathin structures based in amaranth (Amaranthus hypochondriacus) protein isolate through electrospinning. Food Hydrocolloids, 31(2), 289-298. https://doi.org/10.1016/j.foodhyd.2012.11.009

Alehosseini, A., Gómez-Mascaraque, L. G., Martínez-Sanz, M., & López-Rubio, A. (2019a). Electrospun curcumin-loaded protein nanofiber mats as active/bioactive coatings for food packaging applications. Food Hydrocolloids, 87, 758-771. https://doi.org/10.1016/j.foodhyd.2018.08.056

Alehosseini, A., Sarabi-Jamab, M., Ghorani, B., & Kadkhodaee, R. (2019b). Electro-encapsulation of Lactobacillus casei in high-resistant capsules of whey protein containing transglutaminase enzyme. LWT-Food Science and Technology, 102, 150-158. https://doi.org/10.1016/j.lwt.2018.12.022

Arnao, M. B., Cano, A., & Acosta, M. (2001). The hydrophilic and lipophilic contribution to total antioxidant activity. Food Chemistry, 73(2), 239-244. https://doi.org/10.1016/S0308-8146(00)00324-1

Barragán Condori, M., Aro Aro, J. M., Huamaní Meléndez, V. J., & Cartagena Cutipa, R. (2018). Antocianinas, compuestos fenólicos y capacidad antioxidante del mio mio (Coriaria ruscifolia L.). Revista de Investigaciones Altoandinas, 20(4), 419-428. https://doi.org/10.18271/ria.2018.419

Bécquer-Viart, M. A., González-Yaque, J., Fonseca-Fonseca, L. A., Núñez-Figueredo, Y., & Andreu, G. L. P. (2018). Antioxidant and neuroprotective effects of gossypitrin, a flavonoid from Talipariti elatum, against chemical hypoxia-induced PC12 cell death. Journal of Pharmacy & Pharmacognosy Research, 6(2), 72-80. https://www.redalyc.org/journal/4960/496055771002

European Directorate for the Quality of Medicines & HealthCare. (2025). European Pharmacopoeia (11th ed., Cap. 2.9.3 Dissolution of solid dosage forms) [Ediciones en línea]. European Pharmacopoeia Online. https://pheur.edqm.eu/home

Fernández-Perez, A., Iglesias-Guevara, D., Cartaya-Quintero, R., & Arencibia-Sánchez, J. A. (2020). Obtención de un extracto rico en antocianinas a partir de flor de majagua (Talipariti elatum SW). Revista CENIC Ciencias Biológicas, 51(2), 132-140. https://www.redalyc.org/journal/1812/181272273005

Franco, R. F., & Jimenez, P. C. (2025). Pharmacological applications of electrospun nanofibers loaded with bioactive natural compounds and extracts: A systematic review. Drugs and Drug Candidates, 4(1), 8. https://doi.org/10.3390/ddc4010008

Goitia, H., Ferrer, E., & Williams, P. (2019). Síntesis de complejos vo-flavonoides. Estudio de su actividad citotóxica y capacidad antioxidante. Investigación Joven, 6(Especial), 68-69. https://revistas.unlp.edu.ar/InvJov/article/view/6865

Gómez-Mascaraque, L. G., Hernández-Rojas, M., Tarancón, P., Tenon, M., Feuillère, N., Ruiz, J. F. V., ... & López-Rubio, A. (2017). Impact of microencapsulation within electrosprayed proteins on the formulation of green tea extract-enriched biscuits. LWT-Food Science and Technology, 81, 77-86. https://doi.org/10.1016/j.lwt.2017.03.041

González, J., Cuéllar, A., Nossin, E., & Monan, M. (2017). Iron chelating activity of gossypitrin isolated from the petals of Talipariti elatum Sw. (Fryxell) Malvaceae. Journal of Agricultural Studies, 5(1). https://doi.org/10.5296/jas.v5i2.11174

Kokalj Ladan, M., Straus, J., Tavčar Benković, E., & Kreft, S. (2017). FT-IR-based method for rutin, quercetin and quercitrin quantification in different buckwheat (Fagopyrum) species. Scientific Reports, 7, Article 7226. https://doi.org/10.1038/s41598-017-07665-z

Korsmeyer, R. W., Gurny, R., Doelker, E., Buri, P., & Peppas, N. A. (1983). Mechanisms of solute release from porous hydrophilic polymers. International Journal of Pharmaceutics, 15(1), 25-35. https://doi.org/10.1016/0378-5173(83)90064-9

Larkin, P. (2011). Infrared and Raman spectroscopy; principles and spectral interpretation. Wiley.

Lee, J. S., Choi, I., & Han, J. (2021). Mathematical modeling of cinnamon (Cinnamomum verum) bark oil release from agar/PVA biocomposite film for antimicrobial food packaging: The effects of temperature and relative humidity. Food Chemistry, 363, 130306. https://doi.org/10.1016/j.foodchem.2021.130306

Leuci, R., Brunetti, L., Poliseno, V., Laghezza, A., Loiodice, F., Tortorella, P., & Piemontese, L. (2020). Natural compounds for the prevention and treatment of cardiovascular and neurodegenerative diseases. Foods, 10(1), 29. https://doi.org/10.3390/foods10010029

Miranda, M., & Cuellar, A. (2000). Manual de prácticas de laboratorio. Farmacognosia y Productos Naturales. La Habana: Editorial Félix Varela, 70-110.

Mohd Sairazi, N. S., & Sirajudeen, K. N. S. (2020). Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases. Evidence‐Based Complementary and Alternative Medicine, 2020(1), 6565396. https://doi.org/10.1155/2020/8852680

Ordoudi, S. A., de los Mozos Pascual, M., & Tsimidou, M. Z. (2014). On the quality control of traded saffron by means of transmission Fourier-transform mid-infrared (FT-MIR) spectroscopy and chemometrics. Food Chemistry, 150, 414-421. https://doi.org/10.1016/j.foodchem.2013.11.014

Ortega, R., Muñoz, A., Talens, P., & Chiralt, A. (2016). Improvement of properties of glycerol plasticized starch films by blending with a low ratio of polycaprolactone and/ or polyethylene glycol. Food Hydrocolloids, 56, 9-19. https://doi.org/10.1016/j.foodhyd.2015.11.029

Peleg, M. (1988). An empirical model for the description of moisture sorption curves. Journal of Food Science, 53(4), 1216-1217. https://doi.org/10.1111/j.1365-2621.1988.tb13565.x

Reyes, L. F., & Cisneros-Zevallos, L. (2007). Degradation kinetics and colour of anthocyanins in aqueous extracts of purple- and red-flesh potatoes (Solanum tuberosum L.). Food Chemistry, 100(3), 885-894. https://doi.org/10.1016/j.foodchem.2005.11.051

Slinkard, K., & Singleton, V. L. (1977). Total phenol analysis: automation and comparison with manual methods. American Journal of Enology and Viticulture, 28(1), 49-55. https://doi.org/10.5344/ajev.1977.28.1.49

Thaipong, K., Boonprakob, U., Crosby, K., Cisneros-Zevallos, L., & Byrne, D. H. (2006). Comparison of ABTS, DPPH, FRAP, and ORAC assays for estimating antioxidant activity from guava fruit extracts. Journal of Food Composition and Analysis, 19(6-7), 669-675. https://doi.org/10.1016/j.jfca.2006.01.003

Published

2026-01-31

Data Availability Statement

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Section

Original articles

How to Cite

Iglesias, D., Arencibia, J. A., Casariego, A., & Doyharzabal, J. (2026). Electrospinning encapsulation of a majagua flower (Talipariti elatum Sw.) extract in zein for sustained release of bioactive compounds. Revista Gregoriana De Ciencias De La Salud, 3(1), 124-135. https://doi.org/10.36097/rgcs.v3i1.3222

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