La hemoglobina glicada se correlaciona con marcadores inflamatorios de riesgo cardiovascular en pacientes con diabetes mellitus tipo 2
DOI:
https://doi.org/10.36097/rgcs.v3i1.3197Palabras clave:
riesgo cardiovascular, diabetes tipo 2, HbA1c, inflamaciónResumen
La hiperglucemia promueve la inflamación e incrementa el riesgo cardiovascular. El objetivo de este estudio fue analizar la relación entre el control glucémico y marcadores inflamatorios y de riesgo cardiovascular en pacientes con diabetes tipo 2 (DM2). Se realizó un estudio transversal y correlacional que incluyó 300 adultos (240 diabéticos clasificados según sus niveles de HbA1c y 60 controles). Se midieron glucemia, HbA1c, perfil lipídico, fibrinógeno, proteína C reactiva ultrasensible (PCR-us), índice aterogénico plasmático (IAP) y velocidad de sedimentación globular (VSG). Los pacientes con DM2 mostraron niveles más altos de fibrinógeno, PCR-us, IAP y VSG en comparación con los controles y entre los grupos con peor control glucémico (p<0,001). Se observó una correlación positiva significativa entre la HbA1c y todos los biomarcadores evaluados (p<0,0001). Estos hallazgos respaldan el uso de la HbA1c no solo como indicador del control glucémico, sino también como marcador indirecto de riesgo cardiovascular en la DM2.
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Derechos de autor 2026 Pablo Aguirre-Villegas, Adriana Pedreáñez
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